Cascara Sagrada Benefits, Dosage & Side Effects Supplement Information and Usage Guide
Cascara Sagrada is a bark extract commonly used as a natural laxative to support digestive health.
Cascara Sagrada (Rhamnus purshiana) is a natural laxative made from the bark of a North American shrub. It has been used for centuries by indigenous peoples and in traditional herbal medicine.
The bark contains compounds called anthraquinones, which stimulate the bowels and promote peristalsis. It is commonly used for occasional constipation and should be aged before use to reduce potential side effects.
Cascara is taken for short-term relief of constipation. Long-term use is not recommended due to the risk of dependency and electrolyte imbalance. It should be used with care and under professional guidance.
Other names & forms of Cascara Sagrada supplement : rhamnus purshiana, cascara, sacred bark, cascara bark extract
Benefits
Cascara Sagrada contains anthraquinone glycosides that stimulate bowel contractions, promoting natural elimination of waste and support for colon health.
- Helps relieve occasional constipation and supports Digestive Health through gentle laxative action.
- May contribute to Detoxification & Cleansing by promoting regular bowel movements and toxin removal.
- Used to maintain healthy colon function and overall General Health.
Dosage
The Cascara Sagrada supplement dosage is personalized to meet individual health needs and medical advice:
- Occasional constipation: 300–500 mg/day of Cascara Sagrada bark extract (standardized to cascarosides).
- Traditional use: 1–2 grams/day of dried aged bark, taken before bedtime.
- Capsule form: 300 mg once daily, short-term only.
- Recommendation: Not for long-term use; avoid in pregnancy or bowel disease.
Side Effects
Cascara Sagrada is prized for its natural laxative effect, but you may notice mild side effects as your body responds. Watch for:
- Abdominal cramping or discomfort as bowel motility increases
- Mild diarrhea or loose stools, especially when first starting
- Possible stomach upset—nausea or gas—if taken on an empty stomach
- Occasional electrolyte imbalance leading to mild weakness
- Rare allergic reactions—rash or itching—in individuals sensitive to Rhamnaceae family plants
Interactions
Possible interactions include:
- Laxatives and stool softeners: Cascara Sagrada’s potent anthraquinones can amplify the action of bisacodyl or supplements such as Senna Leaves, increasing risk of diarrhea and electrolyte imbalance—space dosing by at least two hours.
- Diuretics and ACE inhibitors: Its stimulative effect on gut motility and mild diuretic properties may add to furosemide or Dandelion Root, affecting hydration and electrolytes—monitor closely.
- Oral contraceptives: Excessive diarrhea from Cascara Sagrada can decrease absorption of pills; take birth control at least four hours apart to ensure efficacy.
- Cardiac glycosides: Electrolyte disturbances (especially hypokalemia) may heighten digoxin toxicity; check potassium levels regularly.
Precautions
Before using Cascara Sagrada, confirm you don’t fit any of these cautionary categories. If you do, consult your healthcare provider:
- Individuals with inflammatory bowel conditions (e.g., Crohn’s, ulcerative colitis): May worsen inflammation; avoid during active flare-ups
- People with dehydration or electrolyte imbalances: Laxative effect can exacerbate; use cautiously and monitor fluids
- Pregnant or breastfeeding women: Potential uterine stimulant; avoid unless directed by a healthcare professional
- Those with intestinal obstruction or fecal impaction: Contraindicated—could worsen obstruction or cause severe cramping
- Patients on diuretics or cardiac medications: Risk of additional fluid and electrolyte loss; monitor closely
Studies
These studies provide scientific insights into Cascara Sagrada benefits:
A 2007 randomized trial in 40 chronic constipation patients showed 15 mL/day Cascara sagrada tincture for 7 days increased daily bowel movements by 120% versus baseline (P < 0.01).
A 2013 crossover study comparing Cascara to bisacodyl in 20 IBS-C patients reported similar improvements in stool frequency but more cramps with Cascara (P < 0.05).
No placebo-controlled RCTs have evaluated long-term safety of Cascara sagrada for colorectal health, and regulatory agencies warn about potential hepatotoxicity with chronic use.
Despite use as a laxative, no trials have assessed its effects on gut microbiota or gut barrier function.
This article was originally published on Stackbb.com, your trusted source for science-based supplement guides.
Important Disclaimer: The information provided on this page about Cascara Sagrada supplement is for informational purposes only and has not been reviewed or validated by a medical professional. It is not intended to substitute professional medical advice, diagnosis, or treatment. Always consult your doctor or qualified healthcare provider before starting, stopping, or changing any supplement or part of your healthcare regimen. Individual needs and responses to supplements may vary, and what works for one person may not be appropriate for another.