Rue Benefits, Dosage & Side Effects Supplement Information and Usage Guide

Rue is a medicinal herb known for its antispasmodic and anti-inflammatory properties, historically used to relieve muscle pain and cramps.

Rue (Ruta graveolens) is a bitter, aromatic herb used historically in European medicine for muscle spasms, joint pain, and digestive issues.

It contains rutin and alkaloids that may support capillary strength and reduce inflammation. Rue has also been used topically for bruises and arthritis discomfort.

Rue is used for muscle relief and vascular health. It should be used cautiously, as high doses can be toxic and it may cause photosensitivity or skin irritation.

Other names & forms of Rue supplement : ruta graveolens, rue herb, rue extract

Benefits

Rue delivers targeted benefits for digestive wellness and women’s health:

• May help alleviate menstrual cramps and support Women's Health and Female Hormone Support & Menopause by reducing uterine spasms.
• Helps support Pain Relief for occasional muscle and joint discomfort through its anti-inflammatory effects.
• May contribute to Digestive Health by reducing mild gastrointestinal spasms.

Dosage

The intake of Rue supplement varies and should be adjusted based on individual factors:

• Digestive and muscle cramp relief: 250–1000 mg/day of Rue (Ruta graveolens) extract.
• Tea (traditional): 0.5–1 gram dried herb steeped for 10 minutes, no more than once daily.
• Use caution: High doses can be toxic and cause photosensitivity.
• Recommendation: Best used under guidance; avoid during pregnancy.

Side Effects

Rue can support menstrual comfort and digestive health, but as you start, mild effects may occur. Watch for:

• Mild gastrointestinal upset—nausea or mild cramps—especially on an empty stomach
• Possible headache or dizziness in sensitive individuals
• Rare photosensitivity—increased sunburn risk—due to furanocoumarins
• Temporary mild uterine contractions—monitor if pregnant
• Occasional skin rash or itching in those with Apiaceae sensitivities

Interactions

Possible interactions include:

• Photosensitizing drugs: Rue’s furanocoumarins may enhance phototoxic reactions with tetracyclines or St. John’s Wort; use sunscreen on exposure.
• Anticoagulant and antiplatelet agents: Its coumarin content can add to warfarin or Garlic, increasing bleeding risk—monitor INR.
• Antispasmodic medications: Rue’s smooth muscle relaxant effects may potentiate dicyclomine; monitor for excessive GI relaxation.
• Sedatives: Potential mild sedation when combined with benzodiazepines or Valerian; use with caution.

Precautions

Before incorporating Rue into your regimen, ensure none of the following apply to you. If they do, consult your healthcare provider:

• Pregnant women: Contraindicated—may induce uterine contractions and miscarriage
• Individuals with liver or kidney disease: Potential hepatotoxicity and nephrotoxicity; avoid or use under supervision
• People with photosensitivity disorders: Risk of severe sunburn; avoid sun exposure
• Those on anticoagulant medications: May increase bleeding risk; monitor clotting parameters
• Patients scheduled for surgery: Discontinue at least two weeks prior—possible interactions with anesthesia and bleeding risk

This article was originally published on Stackbb.com, your trusted source for science-based supplement guides.