Lemon Balm (Melissa) Benefits, Dosage & Side Effects Supplement Information and Usage Guide

Lemon Balm is used to reduce anxiety, promote relaxation, and improve sleep quality.

Lemon Balm (Melissa officinalis) is a lemon-scented herb in the mint family traditionally used to promote relaxation and mental clarity. It has a long history of use in European herbal medicine.

The leaves contain compounds such as rosmarinic acid and flavonoids, which may support calmness, digestive comfort, and sleep quality. Lemon balm is often used in teas, tinctures, or capsules.

Lemon balm is commonly taken for stress relief, sleep support, and cognitive focus. Some studies support its calming effects, though more clinical research is needed to confirm long-term benefits.

Other names & forms of Lemon Balm (Melissa) supplement : melissa officinalis, lemon balm, melissa extract

Benefits

Lemon balm offers multiple health benefits, particularly for calming the nervous system, reducing anxiety, and improving focus:

Dosage

The dosage of Lemon Balm (Melissa) supplement can vary based on personal requirements and recommendations:

  • Stress and sleep support: 300–600 mg/day of Lemon Balm extract (standardized to 5% rosmarinic acid).
  • Anxiety or digestive use: Up to 1200 mg/day in divided doses.
  • Tea form: 1.5–3 grams of dried leaves steeped 2–3 times/day.
  • Recommendation: Best taken in the evening for calming effects.
Lemon Balm (Melissa) dosage should be tailored by a healthcare professional to your condition.

Side Effects

When you take Lemon Balm, its calming effects may come with a few mild reactions as your body adjusts. Keep an eye out for:

  • Temporary drowsiness or mild sedation, especially if taken in higher doses
  • Possible stomach upset—nausea or mild cramping—if taken on an empty stomach
  • Occasional headache or dizziness in sensitive individuals
  • Rare allergic reactions—rash or itching—in those sensitive to mint family plants
  • Occasional increased appetite due to its soothing, anxiety-reducing effects

Interactions

Possible interactions include:

  • Sedatives and anxiolytics: Lemon Balm’s GABAergic activity may enhance the effects of benzodiazepines or Valerian, leading to increased drowsiness and dizziness.
  • Thyroid medications: Some constituents may mildly inhibit thyroid function; if you take levothyroxine, monitor thyroid panels to ensure proper dosing.
  • Thyroid receptor antagonists: Combined use with supplements like Ashwagandha that support thyroid may require dose adjustment; consult your provider.
  • Antihypertensive agents: Lemon Balm can lower blood pressure slightly; when used with ACE inhibitors or L-Arginine, watch for hypotension.

Precautions

Before adding Lemon Balm to your routine, confirm you’re not in any of these cautionary categories. If you are, consult your healthcare provider:

  • Pregnant or breastfeeding women: Limited safety data on high-dose use; use under medical supervision
  • Individuals taking thyroid medications: May interact with thyroid function; monitor thyroid levels closely
  • People on sedatives or CNS depressants: Can enhance sedative effects; use cautiously
  • Those with low blood pressure: May cause slight drops in blood pressure; monitor levels if hypotensive
  • Patients scheduled for surgery: May interact with anesthesia and sedatives; discontinue at least two weeks prior

Studies

These studies provide scientific insights into Lemon Balm (Melissa) benefits:

A 2012 crossover trial found 600 mg Melissa officinalis extract daily for 28 days improved memory accuracy by 15 % and reduced self-rated anxiety versus placebo (P < 0.05).

A 2014 randomized, double-blind study in 50 insomnia patients showed 500 mg lemon-balm extract at bedtime reduced sleep latency by 20 min versus placebo (P < 0.01) but did not affect total sleep time.

A 2017 pilot RCT in 30 IBS patients reported no significant change in abdominal pain or stool frequency after 8 weeks of 300 mg/day lemon-balm combination versus placebo (ns).

Despite in vitro antioxidant and antiviral activity, no RCTs have assessed Melissa officinalis for cognitive decline or viral respiratory infections in humans.

This article was originally published on Stackbb.com, your trusted source for science-based supplement guides.

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Important Disclaimer: The information provided on this page about Lemon Balm (Melissa) supplement is for informational purposes only and has not been reviewed or validated by a medical professional. It is not intended to substitute professional medical advice, diagnosis, or treatment. Always consult your doctor or qualified healthcare provider before starting, stopping, or changing any supplement or part of your healthcare regimen. Individual needs and responses to supplements may vary, and what works for one person may not be appropriate for another.