Nattokinase Benefits, Dosage & Side Effects Supplement Information and Usage Guide

Nattokinase is an enzyme from fermented soy that supports cardiovascular health and promotes healthy blood flow.

Nattokinase is an enzyme extracted from natto, a traditional Japanese food made by fermenting soybeans. It has gained attention for its potential cardiovascular benefits and natural clot-dissolving properties.

This enzyme may help support healthy blood circulation by breaking down fibrin, a protein involved in blood clot formation. As such, it's often used to promote heart health and maintain normal blood flow.

If you're exploring natural ways to support your cardiovascular system, nattokinase offers a unique and well-researched option. It's typically taken in supplement form, often alongside other heart-friendly nutrients.

Other names & forms of Nattokinase supplement : natto enzyme, fermented soy enzyme

Benefits

As a fibrinolytic enzyme, Nattokinase offers circulation and cardiovascular wellness benefits:

  • Circulatory Health: Promotes healthy blood viscosity and may reduce clot-related risks, aiding heart function.
  • Healthy Aging: May help protect blood vessels from oxidative damage, contributing to vascular longevity.
  • Blood Pressure: Some studies suggest nattokinase may support normal blood pressure levels.

Dosage

The Nattokinase supplement dosage is personalized to meet individual health needs and medical advice:

  • Cardiovascular support: 100–200 mg/day (typically 2000–4000 FU) taken once or twice daily.
  • Clot prevention: Often used at 2000 FU twice daily in clinical protocols.
  • Supplement form: Found in capsules standardized by fibrinolytic units (FU), not mg.
  • Recommendation: Take on an empty stomach, at least 1 hour before or 2 hours after meals.
Nattokinase dosage should be tailored by a healthcare professional to your condition.

Side Effects

Nattokinase is generally well tolerated, but since it affects blood clotting, it may lead to specific side effects in some users. Pay close attention if you notice unusual symptoms.

  • Increased risk of bleeding or bruising
  • Headache or dizziness
  • Stomach upset or nausea
  • Allergic reactions in people sensitive to soy

Interactions

Possible interactions include:

  • Anticoagulant and antiplatelet drugs: Nattokinase may enhance blood thinning, increasing the risk of bleeding when combined with medications like warfarin or aspirin.
  • NSAIDs (e.g., ibuprofen): May compound the blood-thinning effect and raise bleeding risk, especially with high doses.
  • Garlic and Ginkgo Biloba: These natural anticoagulants may interact additively with nattokinase.

Precautions

Before using nattokinase, especially if you're on medication or have cardiovascular concerns, consider the following safety notes.

  • People on anticoagulants: Nattokinase may enhance the effects of blood thinners, increasing bleeding risk.
  • Those with bleeding disorders: Avoid unless advised by a physician due to potential clotting interference.
  • Surgery patients: Discontinue use at least two weeks before any surgical procedure.
  • Pregnant or breastfeeding women: Not enough data exists to confirm safety during pregnancy or lactation.

Studies

These studies provide scientific insights into Nattokinase benefits:

A 2011 open-label study in healthy adults reported that nattokinase (2000 FU/day) reduced blood viscosity and systolic blood pressure over 8 weeks (PubMed 21771527).

A 2016 prospective cohort study in hypertensive participants found nattokinase supplementation was associated with a 10% reduction in hypertension risk over 4 years (PubMed 26783394).

This article was originally published on Stackbb.com, your trusted source for science-based supplement guides.

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Important Disclaimer: The information provided on this page about Nattokinase supplement is for informational purposes only and has not been reviewed or validated by a medical professional. It is not intended to substitute professional medical advice, diagnosis, or treatment. Always consult your doctor or qualified healthcare provider before starting, stopping, or changing any supplement or part of your healthcare regimen. Individual needs and responses to supplements may vary, and what works for one person may not be appropriate for another.