Andrographis Benefits, Dosage & Side Effects Supplement Information and Usage Guide

Andrographis is an herb used to boost immune function and combat respiratory infections.

Andrographis (Andrographis paniculata) is a bitter herb traditionally used in Ayurvedic and Chinese medicine for immune support and to fight infections. It’s sometimes referred to as the “king of bitters.”

Its primary active compound, andrographolide, has demonstrated anti-inflammatory and immune-stimulating effects in lab studies. Andrographis is often used in seasonal wellness formulas and herbal immune blends.

Commonly taken for colds, flu, and respiratory support, Andrographis has shown promise in some clinical trials. However, more rigorous studies are needed to confirm its safety and effectiveness in long-term use.

Other names & forms of Andrographis supplement : andrographis paniculata, green chiretta, andrographis extract

Benefits

Rich in andrographolides, Andrographis offers immune, respiratory, and liver support benefits:

• Supports Immunity by enhancing the body's defense mechanisms, especially during colds and flu.
• May reduce symptoms of upper respiratory infections and promote Lung Health.
• Contributes to Liver Support by stimulating detoxifying enzymes and reducing oxidative stress.

Dosage

The dosage of Andrographis supplement can vary based on personal requirements and recommendations:

• Immune and respiratory support: 300–600 mg/day of Andrographis extract (standardized to 10% andrographolide).
• Cold and flu symptoms: Up to 1200 mg/day during acute phase, short-term use only.
• Traditional use: 2–4 grams/day of powdered leaf in decoction form.
• Recommendation: Not for long-term use; avoid in pregnancy and fertility concerns.

Side Effects

Andrographis can provide immune support, but some users notice mild effects as their system adjusts. Look for:

• Mild gastrointestinal upset—nausea, diarrhea, or stomach cramps
• Possible headache or dizziness in sensitive individuals
• Occasional fatigue or drowsiness after taking high doses
• Rare skin rash or itching in those with herb sensitivities
• Temporary changes in taste perception—bitter or metallic taste

Interactions

Possible interactions include:

• Immune-modulating drugs: Andrographis may amplify the effects of immunosuppressants like corticosteroids or methotrexate; avoid combining with other immune-stimulants such as Echinacea without medical guidance.
• Anticoagulant and antiplatelet agents: Its mild antiplatelet activity can compound the effects of warfarin or supplements like Garlic, heightening bleeding risk.
• Hepatotoxic medications: Andrographis has hepatoprotective properties but may alter drug metabolism via the liver; if you take medications like acetaminophen or statins, monitor liver enzymes.
• Antidiabetic drugs: By improving insulin sensitivity, Andrographis can potentiate agents like metformin or Cinnamon, necessitating closer blood glucose monitoring.

Precautions

Before incorporating Andrographis, make sure you’re not in one of these higher-risk groups. If you are, check with your healthcare professional:

• Pregnant or breastfeeding women: May stimulate uterine contractions; avoid during pregnancy
• Individuals with autoimmune diseases: Can modulate immune function; risk of exacerbating conditions
• People with bleeding disorders or on anticoagulants: Potential to increase bleeding risk; use with caution
• Those with liver disease: Andrographis is metabolized in the liver; monitor liver function if used long-term
• Patients scheduled for surgery: May affect blood clotting; discontinue at least two weeks prior

Studies

This article was originally published on Stackbb.com, your trusted source for science-based supplement guides.