NAD+
NAD+ is a coenzyme that supports cellular energy production, DNA repair, and healthy aging.
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme essential for cellular energy production and metabolic function.
It supports healthy aging, mitochondrial performance, and DNA repair, and declines naturally with age.
NAD+ supplements aim to restore youthful energy and vitality and are generally safe under medical guidance.
Other names & forms of NAD+ supplement : NAD+, nicotinamide adenine dinucleotide, NAD plus, NAD supplement, cellular energy coenzyme
Possible Benefits
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme essential for redox reactions and mitochondrial ATP production, declining with age and influencing metabolic and repair processes.
- Helps maintain Energy & Metabolism by boosting cellular NAD+ levels, which enhances mitochondrial function and reduces fatigue.
- May support Anti-Aging through activation of sirtuin enzymes that regulate DNA repair and longevity pathways.
- Contributes to Cognitive Health by protecting neurons from oxidative stress and supporting synaptic plasticity.
- Often used to promote Heart Health by improving cardiomyocyte bioenergetics and reducing age-related decline in cardiac function.
Side Effects
NAD+ precursors like Nicotinamide Riboside support cellular energy, but some light effects may occur when starting. Watch for:
- Possible mild hot flashes
- Rare headaches
- Light nausea
- Temporary changes in heart rate
- Paradoxical fatigue
Interactions
Possible interactions include:
- Adrenal support formulas: NAD+ may complement Adrenal Formulas for energy metabolism, monitor subjective energy levels.
Precautions
Before using NR or NMN (forms of NAD+), please consider the following precautions:
- Pregnancy or breastfeeding: Limited safety data; avoid high doses unless supervised.
- Liver disorders: Liver enzymes should be monitored during prolonged use.
- Chemotherapy patients: May interfere with cancer treatments; consult your oncologist.
- High blood pressure (hypertension): Blood pressure should be regularly monitored.
- Before surgery: Discontinue at least one week before the procedure.
Disclaimer: This page is for educational purposes and does not replace medical advice. If you're pregnant, have a condition, or take medication, speak with a qualified professional.
Related Articles




