NMN

Possible Benefits

NMN (Nicotinamide Mononucleotide) serves as a direct precursor to NAD⁺, boosting mitochondrial function and enhancing cellular energy production.

• Helps support Energy & Metabolism by increasing NAD⁺ levels, which are essential for ATP synthesis.
• May contribute to Anti-Aging through activation of sirtuin enzymes that promote DNA repair and longevity pathways.
• Supports Heart Health by improving cardiomyocyte bioenergetics and resilience against age-related decline.
• Often used to bolster Cognitive Health by safeguarding neuronal mitochondria and reducing neurodegenerative risk.

Side Effects

NMN (Nicotinamide Mononucleotide) boosts cellular NAD+ levels for energy, but during the adaptation phase you may notice mild effects. Watch for:

• Possible mild flushing or warmth sensation
• Occasional headache or lightheadedness
• Temporary mild fatigue as metabolism adjusts
• Rare gastrointestinal discomfort, nausea or cramps
• Very mild changes in sleep quality

Interactions

Possible interactions include:

• Antioxidant therapies: NMN’s NAD+ support complements CoQ10 and resveratrol; monitor overall antioxidant load.

Precautions

Before supplementing with NMN, confirm none of the following apply to you. If they do, consult your healthcare provider:

• Individuals with liver or kidney impairment: Monitor organ function if used long term
• People on chemotherapy or radiation: May interfere with therapies; discuss with oncologist
• Those with hypotension: May cause slight blood pressure changes; monitor regularly
• Pregnant or breastfeeding women: Safety not established; avoid high-dose use
• Patients scheduled for surgery: Discontinue at least one week prior, possible anesthesia interactions

Studies