Chamomile
Chamomile is a flowering herb used for its calming effects, aiding sleep, and digestive relief.
Chamomile (Matricaria chamomilla) is a well-known herb traditionally used for relaxation, sleep support, and digestive comfort. Its dried flowers are commonly brewed into a soothing tea.
Chamomile contains apigenin and other flavonoids that may bind to brain receptors to promote calmness and reduce anxiety. It also has mild anti-inflammatory and antispasmodic effects.
Chamomile is used for stress relief, sleep, and mild gastrointestinal discomfort. Widely regarded as safe, it is supported by some clinical research, though allergic reactions may occur in sensitive individuals.
Other names & forms of Chamomile supplement : matricaria chamomilla, german chamomile, roman chamomile, chamomile flower, chamomile extract
Possible Benefits
Chamomile contains apigenin and bisabolol, compounds that interact with GABA receptors to promote relaxation and support digestive comfort.
- Helps support Sleep Support by reducing the time it takes to fall asleep and improving sleep quality.
- May soothe Digestive Health by relaxing gastrointestinal muscles and reducing spasms.
- Contributes to Nervous System & Stress Relief by calming the mind and reducing mild anxiety.
- Provides mild immune support through its antimicrobial properties, aiding Immunity.
Side Effects
Chamomile can soothe your mind and digestive tract, but some people experience mild effects as they adjust. Keep an eye out for:
- Mild drowsiness or sedation, avoid driving or operating machinery after taking
- Possible mild gastrointestinal upset, nausea or stomach cramps, if taken on an empty stomach
- Occasional allergic reactions, rash, itching, or breathing difficulty, in those sensitive to Asteraceae family plants
- Mild headache or dizziness in sensitive individuals
- Rare mouth or throat irritation when consuming concentrated extracts
Interactions
Possible interactions include:
- Sedative medications and CNS depressants: Chamomile’s apigenin may enhance the effects of benzodiazepines or supplements like Valerian, leading to increased drowsiness and dizziness.
- Anticoagulant and antiplatelet agents: Chamomile contains coumarin-like compounds that may add to warfarin or supplements such as Garlic, raising bleeding risk, monitor INR.
- Cytochrome P450 substrates: Chamomile can inhibit CYP3A4, potentially altering levels of medications like statins or CoQ10; adjust doses and monitor effects.
- Hormone therapies: Mild estrogenic activity may interact with Progesterone or HRT; discuss with your provider.
Precautions
Before you rely on Chamomile for relaxation, check if any of the following apply to you. If they do, consult your healthcare provider:
- Individuals with ragweed or pollen allergies: High risk of cross-reactive allergic reactions; avoid if sensitive
- People taking blood-thinning medications: May increase bleeding risk; monitor clotting parameters closely
- Pregnant or breastfeeding women: Generally safe in tea amounts; high-dose extracts should be used under medical supervision
- Those with gastroesophageal reflux disease (GERD): May exacerbate reflux; take with food or reduce dose
- Patients scheduled for surgery: Discontinue at least two weeks prior, potential interactions with anesthesia and sedation effects
Studies
These studies provide scientific insights into Chamomile benefits:
A 2016 randomized, double-blind trial in 57 generalized anxiety disorder patients showed 500 mg chamomile extract twice daily for 8 weeks reduced HAM-A scores by 45% versus 11% with placebo.
A 2013 crossover study in 34 insomniac adults found 270 mg chamomile extract nightly for 28 days improved sleep quality index scores by 20% versus placebo.
A 2010 double-blind RCT in 60 IBS patients reported 1,500 mg/day chamomile tea for 4 weeks did not significantly change abdominal pain or stool frequency versus control .
Despite in vitro anti-inflammatory effects, no clinical trials have assessed chamomile for allergic or skin conditions in humans.
Disclaimer: This page is for educational purposes and does not replace medical advice. If you're pregnant, have a condition, or take medication, speak with a qualified professional.




