Yohimbe Benefits, Dosage & Side Effects Supplement Information and Usage Guide
Yohimbe is used to enhance libido, improve erectile function, and support athletic performance.
Yohimbe (Pausinystalia yohimbe) is a tree native to West Africa whose bark has traditionally been used as an aphrodisiac and energy booster. It is often found in male enhancement and fat-burning supplements.
The active compound, yohimbine, is an alkaloid that may increase blood flow and stimulate the nervous system by blocking alpha-2 adrenergic receptors. It has been used clinically for erectile dysfunction.
Yohimbe is taken for libido, performance, and fat loss. While some studies support its effects, it may cause side effects and interact with medications, so it should be used with caution under professional supervision.
Other names & forms of Yohimbe supplement : pausinystalia yohimbe, yohimbe bark, yohimbine, yohimbe extract
Benefits
Yohimbe offers targeted health benefits, particularly for libido, circulation, weight loss and energy levels:
- May improve Erectile Dysfunction by enhancing nitric oxide release and penile blood flow.
- May support Weight Loss by promoting lipolysis and increasing metabolic rate.
- Helps boost energy and endurance, contributing to Energy & Metabolism.
- Some users take it to support Nervous System & Stress Relief by enhancing alertness.
Dosage
The Yohimbe supplement dosage is personalized to meet individual health needs and medical advice:
- Libido and fat loss: 5–20 mg/day of Yohimbine HCl (active compound), typically split into 2–3 doses.
- Whole bark extract: Often standardized to 2% yohimbine; 250–500 mg/day total.
- Timing: Take on an empty stomach for fat-burning; not near bedtime due to stimulant effect.
- Recommendation: Use cautiously; avoid in high blood pressure, anxiety, or heart conditions.
Side Effects
Yohimbe can help with blood flow and libido, but some users notice mild side effects as their system adapts. Look out for:
- Mild increased heart rate or palpitations—especially with higher doses
- Possible anxiety or restlessness in sensitive individuals
- Occasional headache or dizziness—particularly when taken on an empty stomach
- Temporary gastrointestinal upset—nausea or stomach cramps
- Rare elevated blood pressure—monitor if you have hypertension
Interactions
Possible interactions include:
- PDE-5 inhibitors and nitrates: Yohimbe’s yohimbine may enhance vasodilation when combined with sildenafil or nitroglycerin, risking severe hypotension and headache.
- Stimulants and caffeine: Its stimulant effects can add to amphetamines or Guarana, increasing anxiety, jitteriness, or palpitations.
- Antidepressants (MAOIs): Yohimbine may interact with MAO inhibitors to raise blood pressure or cause headaches; avoid combining without medical oversight.
- Antihypertensive drugs: Despite its pressor effect, variable responses may occur when used with ACE inhibitors or L-Arginine; monitor blood pressure closely.
Precautions
Before you begin Yohimbe, verify that none of these apply to you. If they do, consult your healthcare professional:
- Individuals with cardiovascular conditions (e.g., arrhythmias, hypertension): May exacerbate symptoms; avoid unless cleared by a cardiologist
- People with anxiety disorders: Can increase anxiety and restlessness; use cautiously
- Those with renal or hepatic impairment: Metabolism and clearance may be affected; adjust dose under supervision
- Pregnant or breastfeeding women: Limited safety data; best to avoid
- Patients scheduled for surgery: Discontinue at least two weeks prior—may interact with anesthesia and affect blood pressure
Studies
These studies provide scientific insights into Yohimbe benefits:
A 2010 meta-analysis of Yohimbe bark extract RCTs (n = 622) found a pooled improvement in erectile function scores of 4.5 points on the IIEF versus placebo (95% CI: 2.1–6.9; P < 0.001) with frequent neuropsychiatric adverse events (headache, anxiety).
A 2005 double-blind trial in 40 athletes showed 15 mg Yohimbine daily for 7 days increased fat oxidation by 20% during exercise but did not improve time-to-exhaustion versus placebo (ns).
A 2000 randomized study of 20 mg Yohimbine in 100 men with mild ED reported only a 12% responder rate versus 4% with placebo (P = 0.07), indicating limited efficacy.
Despite traditional use for weight loss, no large RCTs have evaluated Yohimbe’s effects on body composition or metabolic parameters in humans.
This article was originally published on Stackbb.com, your trusted source for science-based supplement guides.
Important Disclaimer: The information provided on this page about Yohimbe supplement is for informational purposes only and has not been reviewed or validated by a medical professional. It is not intended to substitute professional medical advice, diagnosis, or treatment. Always consult your doctor or qualified healthcare provider before starting, stopping, or changing any supplement or part of your healthcare regimen. Individual needs and responses to supplements may vary, and what works for one person may not be appropriate for another.